CompletedNot Applicable

Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section

Egypt114 participantsStarted 2023-05-15

Plain-language summary

Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block. However, there have not been adequate studies to establish the efficacy of adding hyaluronidase in lateral TAP after cesarean section. Hence, the present study was carried out to evaluate the efficacy of hyaluronidase in different concentrations added to bupivacaine in US-guided bilateral lateral TAP block.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * parturients who aged between 18-40 years old * with ASA physical status grade II and * scheduled for elective CS under spinal anesthesia Exclusion Criteria: * patients with ASA grade III or IV, * refusal to participate, * emergency CS or complicated pregnancy, * those with bleeding disorders or on anticoagulants, * those with severe respiratory and cardiovascular diseases, * having any local infection at the injection site, * history of allergy to one of the used drugs, * obese patients (body mass index ≥ 30 kg/m2).

What they're measuring

the duration of analgesia

Timeframe: 24 hours postoperative

Trial details

NCT IDNCT05671172

SponsorBenha University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-10

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