Block Pressor Response to Intubation (NCT05659212) | Clinical Trial Compass
UnknownNot Applicable
Block Pressor Response to Intubation
102 participantsStarted 2023-01-03
Plain-language summary
Laryngoscopy and endotracheal intubation are necessary for effective control of airway and ventilation, but it has deleterious effects such as hypertension and disrhythmia
Who can participate
Age range23 Years – 40 Years
SexFEMALE
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Inclusion Criteria:
* ASA physical status I-II
* Age between 23 to 40 years
* With airway of Mallampati grade I and II
* Elective diagnostic laparoscopic gynecologic surgery under general anesthesia with endotracheal intubation
Exclusion Criteria:
* Mallampatti grading III and IV, anticipated difficult intubation
* Body mass index (BMI \> 35 kg/m2), full stomach, pregnancy
* Emergency surgery
* History of cardiac or neurological disease or patient with asthma
* History of Hypersensitivity to the study drugs
* Advanced hepatic or renal failure.
* Patients in whom the duration of laryngoscopy lasted more than 20 seconds
* Patient refusal.
What they're measuring
1
Heart rate (HR)
Timeframe: 10 minutes before intubation to one hour after surgery