UnknownNot Applicable

Preoperative Supine Time for Adrenal Venous Sampling

China120 participantsStarted 2023-03-29

Plain-language summary

This study aim to understand whether the length of preoperative supine time would affect the AVS outcome.

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Patients are clinically diagnosed as primary aldosteronism with ARR≥37 (PAC showed as pg/ml, renin showed as μIU/mL) and passed through PA confirmatory tests (PAC-post CCT\>110pg/ml, PAC-post SSIT \>80pg/ml, or PAC-post FST\>60pg/ml). PAC: plasma aldosterone concentration;
✓. Patients with willing for AVS;
✓. Age 18 or above, male or female, with legal capacity.

✕. Patients with suspected adrenocortical carcinoma or pheochromocytoma;
✕. Patients with high risk of adrenal surgery;
✕. Patients have been subtyping to glucocorticoid-suppressible hyperaldosteronism or familial hyperaldosteronism type III;
✕. Patients were diagnosed as Cushing syndrome or subclinical Cushing syndrome;
✕. Patients were treated with glucocorticoids recently;
✕. Patients with whole body or venipuncture area infection;
✕. Patients with venous access thrombosis;
✕. Patients are allergic to iodine;

The rate of complete biochemical remission

Timeframe: At 6 months of follow-up

NCT IDNCT05658705

SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-29

Liu Zhen jie, MD,PhD