Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block (NCT05654519) | Clinical Trial Compass
CompletedNot Applicable
Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block
Turkey (Türkiye)80 participantsStarted 2022-01-01
Plain-language summary
Adequate pain management following total hip arthroplasty (THA) is a key component for patient satisfaction and early ambulation. However, due to the complexity of the innervation of the hip joint, the most appropriate anaesthetic and analgesic technique for THA remains unclear. A femoral nerve block is commonly performed and well established but is associated with motor weakness. Recently, the pericapsular nerve group (PENG) block has been introduced as an effective choice which targets the articular branches of the hip. The quadratus lumborum block (QLB) is a relatively new regional block that has been reported to provide effective analgesia for THA.
The main objective of this study is to compare the effectiveness of the ultrasound-guided PENG block technique compared to QLB block in terms of efficacy of pain control and the safety profile after total hip arthroplasty under spinal anesthesia.
Who can participate
Age range
40 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Physical status according to American Society of Anesthesiologists (ASA ) I-III
Exclusion Criteria:
* Younger than 40 years old and older than 85
* Patients undergoing general anesthesia
* Allergy or intolerance to one of the study medications
* Infection of the skin at the site of the needle puncture,
* Patients who do not accept the procedure
* History of bleeding diathesis
* ASA IV,
* Chronic gabapentin/pregabalin,opioid use
* Hepatic or renal insufficiency
* Previous operation on the same hip
* BMI \>40
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pain scores
Timeframe: Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours
2
Opioid consumption
Timeframe: Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours