GRIPonMASH will assist (primary) health care providers clinicians to implement the latest patient care pathway, as described by the European Association for the Study of the Liver (EASL), to identify patients at risk of severe metabolic dysfunction-associated steatotic liver disease (MASLD) and to raise awareness. The primary objective is to implement a transmural patient care pathway, in order to identify patients with MASLD and its progressive form metabolic dysfunction-associated steatohepatitis (MASH) in primary care centres and clinics in 10 European countries.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Prevalence of liver steatosis and MASLD estimated by FibroScan CAP in patients at risk
Timeframe: Baseline
Prevalence of liver fibrosis estimated by FibroScan LSM in patients at risk
Timeframe: Baseline
Prevalence of at-risk MASH estimated by FAST score in patients at risk
Timeframe: Baseline
*Subset of patients: prevalence of MASH in patients at risk
Timeframe: 16 or 30 weeks
Comparison of the prevalence of MASLD, liver fibrosis and (at-risk) MASH between the participating countries
Timeframe: Baseline (1-3) to 16/30 weeks for biopsy-confirmed MASH (4)
Evaluate added value of a 2-step pathway as compared to FibroScan only for detection of high-risk patients
Timeframe: Baseline