CompletedNot Applicable

A Clinical Simulation Study of a Test Material on the Anterior Nares

United States50 participantsStarted 2022-03-07

Plain-language summary

The objective of this study is simulate the clinical use of a test material within a 24h window. Efficacy will be simulated as the capacity of the material to reduce or clear the anterior nares bacterial population from opportunistic pathogens (e.g. Staphylococcus Aureus, Escherichia Coli, etc).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Subject is male or female between 18 to 55 years of age;
. Subject has normal nasal passage;
. Subject has not history of chronic nasal passage disease (chronic rhinitis, chronic sinusitis).
. Subject is willing to have materials applied and follow the protocol;
. Subject agrees to avoid exposure of the test sites to any chemical product and to refrain from touching the area of application.
. Subject agrees to refrain from getting the application site wet and scrubbing or washing the test area with soap or applying powders, lotions or personal care products to the area during the course of the study;
. Subject agrees not to introduce any new cosmetic or toiletry products during the study;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Colony Forming Units

Timeframe: up to 24 hours following application

Trial details

NCT IDNCT05617729

SponsorCenter for Innovation and Research Organization

Sponsor typeNETWORK

Study typeINTERVENTIONAL

Primary completion2022-03-18

View on ClinicalTrials.gov More Colonization, Asymptomatic trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Subject is male or female between 18 to 55 years of age;
. Subject has normal nasal passage;
. Subject has not history of chronic nasal passage disease (chronic rhinitis, chronic sinusitis).
. Subject is willing to have materials applied and follow the protocol;
. Subject agrees to avoid exposure of the test sites to any chemical product and to refrain from touching the area of application.
. Subject agrees to refrain from getting the application site wet and scrubbing or washing the test area with soap or applying powders, lotions or personal care products to the area during the course of the study;
. Subject agrees not to introduce any new cosmetic or toiletry products during the study;

A Clinical Simulation Study of a Test Material on the Anterior Nares

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

A Clinical Simulation Study of a Test Material on the Anterior Nares

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

Exclusion criteria