RecruitingNot Applicable

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

United States1,650 participantsStarted 2023-01-01

Plain-language summary

The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. At least 18 years of age or older of either sex (and all genders).
✓. Chronic pain (pain that occurs on at least half of the days of 3 months or more).
✓. Past-month average pain intensity score of at least 3/10.
✓. Ability to adhere to and complete study protocols.

Exclusion criteria

✕. Inability to provide informed consent.
✕. Cognitive impairment, non-English speaking, or psychological factors that would preclude comprehension of material and/or full participation in the study including group treatment.
✕. Active suicidality at screening.
✕. Study staff may exclude individuals with a known history of disruptive behavior to minimize contamination of the learning environment for an entire treatment cohort.
✕. Receipt of either study treatment in the past 3 months.

What they're measuring

Pain Intensity

Timeframe: 1 months

Pain Intensity

Timeframe: 2 months

Pain Intensity

Timeframe: 3 months

Pain Intensity

Timeframe: 6 months

Pain Interference

Timeframe: 1 month

Pain Interference

Timeframe: 2 months

Pain Interference

Timeframe: 3 months

Pain Interference

Timeframe: 6 months

Trial details

NCT IDNCT05612750

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-05-01

Contact for this trial

Emma A Adair, BS

6097448937 eadair@stanford.edu

View on ClinicalTrials.gov More Pain, Chronic trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. At least 18 years of age or older of either sex (and all genders).
✓. Chronic pain (pain that occurs on at least half of the days of 3 months or more).
✓. Past-month average pain intensity score of at least 3/10.
✓. Ability to adhere to and complete study protocols.

Exclusion criteria

✕. Inability to provide informed consent.
✕. Cognitive impairment, non-English speaking, or psychological factors that would preclude comprehension of material and/or full participation in the study including group treatment.
✕. Active suicidality at screening.
✕. Study staff may exclude individuals with a known history of disruptive behavior to minimize contamination of the learning environment for an entire treatment cohort.
✕. Receipt of either study treatment in the past 3 months.