Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance (NCT05602688) | Clinical Trial Compass
CompletedNot Applicable
Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
Pakistan102 participantsStarted 2023-01-03
Plain-language summary
This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion Criteria:
* Healthy individuals, aged 18 - 65 years
* Individuals suffering from moderate degree of depression, anxiety, and stress with DASS scores ≥14, ≥10, and ≥19, respectively, or individual with sleep problems with Pittsburgh Sleep Quality Index (PSQI) score ≥5.
* Willing to participate in the study
Exclusion Criteria:
* Current use of prescribed medication or supplements for neuropsychiatric and sleep disorders
* Known history of neuropsychiatric or sleep disorders
* Current use or history of illicit substances misuse
* History of any allergic reactions to ingredients of the Lemon Balm Extract
* Hypertension (systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90, or other cardiovascular disease
* Hyperthyroidism or Diabetes mellitus or cancer
* Use of blood thinners like Coumadin (warfarin) or Plavix (clopidogrel), Glaucoma medications like Travatan (travoprost), Chemotherapy drugs like tamoxifen and Camptosar (irinotecan)
* Severe medical problem, which in the opinion of the investigator would pose a safety risk to the subject