UnknownNot Applicable

Changes of Clinical Characteristics and Tear Film Biomarkers Following FS-LASIK

China60 participantsStarted 2022-10-31

Plain-language summary

to analyze the clinical and tear molecular profile up to 6 months after FS-LASIK surgery

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. active ocular infection, ocular inflammation, active ocular allergy, severe blepharitis or obvious inflammation of the eyelid margin.
✕. Pregnant and lactating women, or those planning a pregnancy over the course of the study
✕. Uncontrolled systemic disease
✕. Suffer from diseases that may affect corneal nerves, such as keratoconus, trigeminal neuralgia, allergic conjunctivitis, etc.

ocular surface disease index (OSDI)

Timeframe: from Pre-surgery to 6 months after surgery

Tear break-up time (TBUT)(s)

Timeframe: from Pre-surgery to 6 months after surgery

Corneal fluorescein staining (CFS)

Timeframe: from Pre-surgery to 6 months after surgery

Schirmer Ⅰ test (SⅠt) (mm/5 minutes)

Timeframe: from Pre-surgery to 6 months after surgery

NCT IDNCT05601011

SponsorPeking University Third Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-10-19

Hong Qi, M.D.