Patient Self-sampling of HPV to Screen for Cervical Cancer

Inclusion Criteria: * Appointment at Mayo Clinic Rochester in Gynecology Colposcopy Clinic or ICS (integrated community specialty) Colposcopy Clinic (will always include a speculum exam). * Appointment at Mayo Clinic Rochester in Gynecology Clinic for indication that will already include a speculum exam (e.g., cervical cancer screening or IUD insertion). Exclusion Criteria: * Excluded if self-reported as currently menstruating, pregnant, or within 3 months following pregnancy. * Excluded if no cervix (history of total hysterectomy). * Excluded if moderate to heavy vaginal bleeding on the day of the visit. * Excluded if reason for visit in Gynecology Clinic is abnormal vaginal discharge. * Exclude patients who are on Gynecology Colposcopy Clinic for LEEP (loop electrosurgical excision procedure). * Exclude if any use of over-the-counter or prescription vaginal cream for vaginal infection or prescription vaginal estrogen cream for at least two days before using the Evalyn Brush. (Vaginal contraceptives, condoms and water-based lubricants can be used as normal.)