A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic of GSK1070806 After a Single Intravenous Dose in Healthy Male and Female Caucasian, Chinese and Japanese Participants Aged 18 to 65 Years of Age Inclusive

Inclusion Criteria: * Participants who are overtly healthy as determined by medical evaluation including medical history, physical examination, laboratory tests and cardiac monitoring \[12-lead Electrocardiogram (ECGs)\] * Between 18 and 65 years of age inclusive, at the time of signing the informed consent * Body weight within the range 45 - 100 kilograms (kg) and body mass index (BMI) within the range 18-32 kilogram/meter square (kg/m\^2) (inclusive) * A female participant is eligible to participate if she is not pregnant or breastfeeding, and one of the following conditions applies: * Is a woman of non-childbearing potential (WONCBP) OR * Is a woman of childbearing potential (WOCBP) and using a contraceptive method that is highly effective \[with a failure rate of less than 1 percent (\<1%) per year\], with low user dependency * Capable of giving signed informed consent * Participants of Japanese ancestry are eligible based on meeting all of the following: * Healthy male and female participants born in Japan * Descendants of four ethnic Japanese grandparents and two ethnic Japanese parents * Have lived outside Japan for less than 10 years at the time of screening * Chinese participants are eligible based on meeting all of the following: * Healthy male and female participants born in mainland China, Hong Kong, Macau or Taiwan * Descendants of four ethnic Chinese grandparents and two ethnic Chinese parents * Have lived outside mainland China, Hong Kong, Macau or Taiwan for …