CompletedNot Applicable

Determination of Liquid Flavor and Nicotine Form Outcomes

United States13 participantsStarted 2023-07-21

Plain-language summary

The purpose of this research study is to find out how different types of electronic cigarette/vape e-liquids with differing sweetness and forms of nicotine affect blood nicotine levels, use behavior (how people puff), and how people feel.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion Criteria: * healthy (determined by self-report) * between the ages of 18-65 * willing to provide informed consent * use cigarettes, e-cigarettes, or both * able to attend the lab and abstain from tobacco/nicotine as required and must agree to use designated products according to study protocol Exclusion Criteria: * women if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening * existence of any condition contraindicated for this study protocol as determined by study leadership Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.

What they're measuring

Change in plasma nicotine concentration

Timeframe: Baseline (approx 90 min after session start) to after final product usage (up to 165 min)

Puff volume

Timeframe: Through the final product use (up to 165 min)

Puff duration

Timeframe: Through the final product use (up to 165 min)

Challenge paradigm latency

Timeframe: at the end of the challenge paradigm, approx. 165 min

Challenge paradigm puffs

Timeframe: at the end of the challenge paradigm, approx. 165 min

Trial details

NCT IDNCT05587504

SponsorVirginia Commonwealth University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-24

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