Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Inclusion Criteria: * If not of legal age or circumstance to provide independent informed consent as determined by site standard operating procedures (SOPs) and consistent with institutional review board/ethics committee (IRB/EC) policies and procedures: Parent/legal guardian is willing and able to provide written informed consent for potential participant's study participation; in addition, when applicable per IRB/EC policies and procedures, potential participant is willing and able to provide written assent for study participation. * If of legal age or circumstance to provide independent informed consent as determined by site SOPs and consistent with IRB/EC policies and procedures: Potential participant is willing and able to provide written informed consent for study participation. Note: All sites must follow all applicable IRB/EC policies and procedures. * Assigned female sex at birth, as determined by the site investigator based on participant and parent/guardian report and available medical records * Age less than 18 years of age at entry Note: Neonates (defined as children who are 28 days of age or younger \[≤28 days of age\]) may be allowed to enroll after CMC and SMC evaluation of safety and PK data at the interim analysis. * Weight greater than or equal to 4 kg at entry * Has confirmed or probable intrathoracic (pulmonary) RR-TB and/or any form of extrathoracic (extrapulmonary) RR-TB (other than stage 2 or 3 TB meningitis, which is exclusionary) * Confirmed …