The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section. Parturients who planned for a caesarean delivery using combined spinal-epidural anaesthesia with a request for postoperative anaesthesia were randomly divided into four groups (A, B, C and D). When the surgery was completed, the parturients in groups A, B, C and D were administered 2 mg morphine, 0.25mg/kg of esketamine, 0.25mg/kg of esketamine plus 2 mg morphine sulfate and 0.25mg/kg of esketamine plus 1 mg morphine through the epidural catheters, respectively. The postoperative pain at rest, pain with movement, the number of rescue analgesics and adverse effects were evaluated for 48 h after caesarean delivery.
Age range
20 Years – 32 Years
Sex
FEMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Postoperative pain score at rest
Timeframe: Two hours after caesarean delivery
Postoperative pain score at rest
Timeframe: Four hours after caesarean delivery
Postoperative pain score at rest
Timeframe: Eight hours after caesarean delivery
Postoperative pain score at rest
Timeframe: Twelve hours after caesarean delivery
Postoperative pain score at rest
Timeframe: Twenty-four hours after caesarean delivery
Postoperative pain score at rest
Timeframe: Forty-eight hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Two hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Four hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Eight hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Twelve hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Twenty-four hours after caesarean delivery
Postoperative pain score with movement
Timeframe: Forty-eight hours after caesarean delivery
number of rescue analgesics required
Timeframe: within Forty-eight hours of surgery