A Study of LY3819469 in Participants With Elevated Lipoprotein(a) [Lp(a)]

Inclusion Criteria: * Participants must be at least 40 years old at the time of signing the informed consent. * Participants with Lp(a) ≥175 nmol/L at screening, measured at the central laboratory * Participants on the following medications according to local practice must be on a stable regimen for at least 4 weeks prior to screening and randomization and expected to remain on a stable regimen through the end of the Treatment and Assessment Period: * lipid-lowering drugs * testosterone, estrogens, anti-estrogens, progestins, selective estrogen receptor modulators, or growth hormone * Have a body mass index within the range 18.5 to 40 kilogram/square meter (kg/m²), inclusive. Male and/or Female * Males who agree to use highly effective/effective methods of contraception may participate in this trial. * Women not of childbearing potential (WNOCBP) may participate in this trial. Exclusion Criteria: * Have a history or presence of an underlying disease, or surgical, physical, medical, or psychiatric condition that, in the opinion of the investigator, would potentially affect participant safety within the study or interfere with participating in or completing the study or with the interpretation of data. * Any of the following, or other events indicating unstable medical condition in the opinion of the investigator, within 3 months of randomization: * major surgery * coronary, carotid, or peripheral arterial revascularization * stroke or transient ischemic atta…