Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function

Inclusion Criteria: * Age of 18 years or older * Scheduled for total hip replacement surgery under general anaesthesia * Informed consent obtained Exclusion Criteria: * Insufficient control of the Dutch language to read the patient information and to fill out de questionnaires * Known or suspected hypersensitivity to rocuronium or sugammadex * Deficiency of vitamin K dependent clotting factors or coagulopathy * Severe renal disease (creatinine clearance \<30 ml/min), including patients on dialysis * Severe liver disease (Child-Pugh Classification C) * Known or suspected neuromuscular disorders impairing neuromuscular function * Women who are or may be pregnant or currently breastfeeding * Chronic use of psychotropic drugs * Use of immunomodulatory medication