CompletedNot Applicable

Impacts of Oral Irrigation in Orthodontic Patients

Turkey (Türkiye)30 participantsStarted 2018-03-01

Plain-language summary

The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine interleukin (IL)-1β, IL-10, matrix metalloproteinase (MMP)-1, MMP-8 levels in gingival crevicular fluid of orthodontic patients. The null hypothesis was that oral irrigators would be effective compared to interdental brush in the oral care of individuals who are orthodontic patients.

Who can participate

Age range12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Being over 12 years old. * Having at least 20 permanent teeth with bands or brackets. * Finished phase I periodontal treatment. * Bleeding below 10% during probing. * No pocket depth of more than 5 mm. * Not receiving any treatment other than orthodontic treatment during the study. * Absence of removable or fixed prosthetic restorations. * Absence of any systemic disease (hepatic, renal, hematologic, cardiovascular). * Agreeing not to use any non-study mouthwash throughout the study. Exclusion Criteria: * Performing poor cooperation. * Having diseases associated with bacteriemia. * Used antibiotics and anti-inflammatory drugs for any purpose for a long time. * Having diabetes. * Smoking habits. * Having a physical or mental problem that affects manual dexterity. * Using medication that could affect gingival health (such as dilantin, calcium channel blocker, cyclosporine, and anticoagulant).

What they're measuring

GCF (gingival crevicular fluid) level of IL-1β as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of IL-10 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of MMP-1 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of MMP-8 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

Trial details

NCT IDNCT05562986

SponsorOndokuz Mayıs University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-08-01

View on ClinicalTrials.gov More Oral Hygiene trials

Plain-language summary

Who can participate

Age range12 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

GCF (gingival crevicular fluid) level of IL-1β as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of IL-10 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of MMP-1 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year

GCF (gingival crevicular fluid) level of MMP-8 as a marker of gingival inflammation

Timeframe: through study completion, an average of 1 year