Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors

Inclusion Criteria: * Primary cancer diagnosis of breast, prostate, or colorectal cancer * Completion of all cancer-related treatment \> than 6 months prior and \< 5 years prior to enrollment * Ability and willingness to participate in a supervised exercise program * All participants will be required to obtain a signed physician clearance to participate in exercise form prior to enrollment Exclusion Criteria: * Presence of a secondary active cancer diagnosis or metastatic disease * Any current cancer treatment (including hormonal treatment) or planned cancer treatment in the next 5 months * Greater than 100 min of self-reported regular exercise per week * BMI \< 18.5 (underweight) * Any significant metabolic condition, such as diabetes. Individuals with pre-diabetes or metabolic syndrome will not be excluded, but this information will be recorded. * Any medical condition that would impact the safety of, or participation in, an exercise program or exercise testing, including: * Orthopedic conditions such as advanced osteoarthritis, mobility-limiting amputations or chronic injuries, or mobility-limiting acute orthopedic injuries * Advanced rheumatoid arthritis or chronic widespread pain conditions such as fibromyalgia * Pulmonary conditions such as chronic obstructive pulmonary disease, emphysema, or interstitial lung disease * Known cardiovascular disease, uncontrolled hypertension, or new cardiac event within the past 6 months