RecruitingNot Applicable

Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries

Egypt76 participantsStarted 2022-11-01

Plain-language summary

Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.

Who can participate

Age range19 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologists physical status I or II * Elective unilateral lower limb orthopedic surgery with tourniquet under spinal anesthesia Exclusion Criteria: * Pregnant females * Body mass index ≥ 35 kg/m2 * Allergy to ketorolac * Had renal, asthmatic, vascular (Raynaud's syndrome) disease, hematological anemias * Had any history of gastrointestinal tract inflammation, bleeding, ulceration, or perforation besides * Edema in the operated limb grade ≥ 3

What they're measuring

The postoperative analgesic duration

Timeframe: within 24 hours after the surgery

Trial details

NCT IDNCT05543785

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-05-30

Contact for this trial

Maha AboZeid, MD

02-01019216192 mahazed@mans.edu.eg

View on ClinicalTrials.gov More Postoperative Pain, Acute trials