Remote State Representation in Early Psychosis (NCT05538832) | Clinical Trial Compass
CompletedEarly Phase 1
Remote State Representation in Early Psychosis
United States152 participantsStarted 2022-07-27
Plain-language summary
The purpose of this study is to examine state representation in individuals aged 18-30 who have been diagnosed with a psychotic illness, as well as young adults who do not have a psychiatric diagnosis. State Representation is our ability to process information about our surroundings. The investigators will complete some observational tests as well as a cognitive training clinical trial.
Who can participate
Age range18 Years – 30 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
INCLUSION CRITERIA
All Participants:
* Between the ages of 18-30 at the time of screening
* Fluent in spoken and written English, in that the participant learned to speak English before the age of 12 or is able to demonstrate fluency in conversation with study staff
* Has an outpatient status and no hospitalization for psychiatric reasons for at least 1 month prior to participant
* Has access to a computer with internet connection
* Has a United States address as permanent residence
* Estimated IQ at or above 70, as estimated by the cognitive assessments
Early Psychosis Participants:
* Diagnosis of one of the following conditions (confirmed via interview): schizophrenia; schizoaffective disorder; schizophreniform disorder; Psychosis not otherwise specified (NOS); major depressive disorder with psychotic features; bipolar disorder with psychotic features
* Willing to share contact with a clinical provider
EXCLUSION CRITERIA
All participants:
* History of severe substance use in the past 3 months (determined by interview)
* Unable to demonstrate capacity to consent to research, in the judgment of the study team
* Diagnosed with a neurological disorder that would impede participation in the study or would put the participant at additional risk by participating, in the opinion of the PI/CO-Is
* Previous clinically significant head injury or prolonged unconsciousness
* Significant cognitive training experience in the past 6 months
* Meets criteria for clinical risk of suici…
What they're measuring
1
Change in Performance of Dot Pattern Expectancy (DPX) Task Variant
Timeframe: Baseline, Immediately after the intervention, 5 month follow up
2
Change in Performance of Bandit Task Variant
Timeframe: Baseline, Immediately after the intervention, 5 month follow up