The Efficacy & Safety of rTMS for Upper-limb Motor Function Recovery in Subcortical and Brainstem… (NCT05535504) | Clinical Trial Compass
TerminatedNot Applicable
The Efficacy & Safety of rTMS for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke
Stopped: Due to difficulty in patient recruitment
South Korea60 participantsStarted 2023-01-02
Plain-language summary
The purpose of this study is to evaluate the efficacy and safety of repetitive transcranial magnetic stimulation applied with an electromagnetic therapy stimulator 'ALTMS-A' for upper-limb motor function recovery with the sham control group for those who need upper-limb rehabilitation treatment for subcortical and brainstem stroke
Who can participate
Age range19 Years – 80 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 19-80 years old
* Radiologically confirmed ischemic stroke with subcortical and brainstem lesions within 90 days
* Fugl-Meyer assessment scale (upper extremity) \> 15
* Mini-mental status exam (the Korean version) \> 14 with appropriate cognitive function
* Written informed consent
Exclusion Criteria:
* Fugl-Meyer assessment scale (wrist) \< 1 or Fugl-Meyer assessment scale (hand) \< 1
* Hemorrhagic stroke or traumatic brain injury
* Cerebellar stroke
* Previous history of stroke
* Traumatic brain injury
* Previous history of brain surgery
* Need for intensive care due to complications associated with stroke (e.g. pneumonia, infection, hemodynamic instability)
* History of psychological or neurological diseases
* History of pain or muscular weakness of upper limbs which may interfere with rehabilitation
* History of seizure or epilepsy
* Aphasia
* Skin lesions in the stimulation site of scalp
* Intracranial metal implant
* Inability to receive regular physical or occupational therapy
* Disagreement to use contraception in women of childbearing age