Active — Not RecruitingNot Applicable

Japan Post Marketing Surveillance of the GORE® CARDIOFORM Septal Occluder

Japan300 participantsStarted 2022-10-03

Plain-language summary

The purpose of this post-marketing surveillance is to evaluate the effectiveness and safety of GORE® CARDIOFORM Septal Occluder under the post-marketing setting in Japan.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with cryptogenic stroke (including transient ischemic attack with positive head imaging findings) * Diagnosed with a PFO * Note: Additional Inclusion Criteria may apply Exclusion Criteria: * N/A

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

PFO Closure Rate

Timeframe: 12 months

Rate of Conversion to surgical procedure

Timeframe: Discharge

Incidence rate of post-procedure ischemic stroke events

Timeframe: 36 months

Device success

Timeframe: 36 months

Incidence rate of post-procedure adverse events and/or device issues

Timeframe: 36 months

Incidence rate of device- and procedure-related events within 30 days post procedure

Timeframe: 30 days

Trial details

NCT IDNCT05529901

SponsorW.L.Gore & Associates

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2029-08

View on ClinicalTrials.gov More Stroke trials

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

PFO Closure Rate

Timeframe: 12 months

Rate of Conversion to surgical procedure

Timeframe: Discharge

Incidence rate of post-procedure ischemic stroke events

Timeframe: 36 months

Device success

Timeframe: 36 months

Incidence rate of post-procedure adverse events and/or device issues

Timeframe: 36 months

Incidence rate of device- and procedure-related events within 30 days post procedure

Timeframe: 30 days