RecruitingNot Applicable

Mode of Sedation During Endovascular Treatment of Vertebrobasilar Stroke

Germany128 participantsStarted 2022-10-01

Plain-language summary

Optimal anesthetic mode is not established for patients with vertebrobasilar stroke undergoing endovascular treatment. We want to investigate whether a procedural sedation mode approach is feasible compared to general anesthesia

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Decision for thrombectomy according to local protocol for acute recanalizing stroke treatment
✓. Age 18 years or older, either sex
✓. National Institutes of Health Stroke Scale (NIHSS) ≥ 4
✓. Acute ischemic stroke in the posterior circulation with isolated or combined occlusion of vertebral artery (VA) and basilar artery (BA)
✓. Informed consent by the patient him-/herself or his/her legal representative obtainable within 72 h of treatment (deferred consenting procedure)

Exclusion criteria

✕. Intracerebral hemorrhage
✕. Coma on admission (Glasgow Coma Scale ≤ 8)
✕. Severe respiratory instability, loss of airway protective reflexes or vomiting on admission, where primary intubation and general anesthesia is deemed necessary
✕. Intubated state before randomization
✕. Severe hemodynamic instability (e.g. due to decompensated cardiac insufficiency)

What they're measuring

Functional outcome as measured by modified Ranking Scale (mRS) after admission.

Timeframe: 90 days +/- 2 weeks

Trial details

NCT IDNCT05525325

SponsorUniversity Hospital Heidelberg

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-01

Contact for this trial

Min Chen, MD

0049/6221/7504 min.chen@med.uni-heidelberg.de

View on ClinicalTrials.gov More Stroke Thrombectomy trials