A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation

Inclusion Criteria: * Completed definitive chemoradiation for Stage II or greater, histologically proven cancer of the oral cavity, oropharynx, hypopharynx, pharynx or larynx with a curative intent * Cognitive function adequate to understand and execute the elements of the protocol * Willingness and ability to return to Mayo Clinic for follow-up care per protocol * Resolution of acute dermatitis (skin must be intact without evidence of inflammation, infection or desquamation) as a result of chemoradiotherapy (CRT) * Must demonstrate oropharyngeal competency that would allow some oral intake Exclusion Criteria: * Prior surgery, radiation, chemotherapy, or immunotherapy for head or neck cancer * Acute radiation dermatitis, unhealed surgical wounds or surgical flap less than 2 months post-operative * Acute facial infection * Active congestive heart failure (CHF) or pulmonary edema * Symptomatic carotid artery disease or bradycardia * Increased intracranial pressure * History of multiple cerebrovascular accidents (CVAs) or transient ischemic attacks (TIAs) * \> 50% internal carotid artery (ICA) blockage * Upper quadrant deep vein thrombosis * Known esophageal obstruction * Percutaneous endoscopic gastrostomy (PEG) tube dependence with no oral intake * Women of child-bearing potential * (Active) pregnancy