In an aging population, cataract and presbyopia become increasingly common. A cataract is the opacification of the natural crystalline lens inside a person's eye, causing reduction of vision. Presbyopia is an age related condition resulting in loss of reading/near vision which results in requiring reading glasses. Astigmatism is a common condition characterized by an abnormal cornea (the clear tissue at the front of the eye) which results in blurred distance and near vision, again requiring glasses. Cataract surgery is the most common elective surgery worldwide for patients over 65. It is composed of removal the cataract and insertion of a new intraocular lens (IOL). Currently only monofocal IOLs are available on the National Health Service (United Kingdom) - meaning they give good distance or near vision. The majority of patients opt for good distance vision with glasses to read. The investigators are trialling insertion of a new Extended Depth of Focus (enhanced aspheric) Toric IOL (EDoF Toric IOL), which treats all 3 conditions - cataract, presbyopia and astigmatism. All patients attending St Thomas' hospital for treatment of cataracts, who have presbyopia and astigmatism will be considered for invitation to the study. Patients who participate in the study will be randomly selected to receive either the new IOL - the TECNIS Eyhance Toric II IOL, or a well-established IOL the Alcon Acrysof IQ Toric IOL during cataract surgery. Insertion of the Alcon Acrysof IQ Toric IOL is known to treat cataract and astigmatism but not presbyopia. Patients will be assessed and have their surgery performed at St Thomas' Hospital London. They will have 7 appointments over 12 months, plus surgery. The investigators hope to demonstrate better distance, intermediate and near vision and increased spectacle independence in the TECNIS Eyhance Toric II IOL group. EDoF Toric IOLs have the potential to transform cataract surgery outcomes for patients in the NHS.
Age range
18 Years – 100 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in Refractive Error from baseline to 6 weeks
Timeframe: 6 weeks after cataract surgery
Change in Refractive Error from baseline to 6 months
Timeframe: 6 months after cataract surgery
Change in Visual acuity from baseline to 6 weeks
Timeframe: 6 weeks after each cataract surgery
Change in Visual acuity from baseline to 6 months
Timeframe: 6 months after each cataract surgery
Change in Patient Satisfaction from baseline to 6 weeks
Timeframe: 6 weeks after each cataract surgery
Change in Patient Satisfaction from baseline to 6 weeks
Timeframe: 6 weeks after each cataract surgery
Change in Patient Satisfaction from baseline to 6 weeks
Timeframe: 6 weeks after each cataract surgery
Change in Patient Satisfaction from baseline to 6 months
Timeframe: 6 months after each cataract surgery
Change in Patient Satisfaction from baseline to 6 months
Timeframe: 6 months after each cataract surgery
Change in Patient Satisfaction from baseline to 6 months
Timeframe: 6 months after each cataract surgery
Change in rotational stability of Intraocular lens relative to its intended angle of insertion from baseline to 6 weeks
Timeframe: 6 weeks after each cataract surgery
Change in rotational stability of Intraocular lens relative to its intended angle of insertion from baseline to 6 months
Timeframe: 6 months after each cataract surgery
Patient related cost benefits in terms of spectacle expenditure.
Timeframe: 6 months after second eye cataract surgery