This trial studies the efficacy and safety of cryoablation in patients with low risk, early stage breast cancer. Cryoablation is a method of killing a tumor by freezing it. The standard approach for patients with this kind of cancer is a lumpectomy. This study will review the safety of the cryoablation procedure initially, followed by comparing cryoablation to lumpectomy in order to see if the cryoablation results in better disease control, complication rates, and quality of life.
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Safety Lead-In: Number of treatment-related complications
Timeframe: Assessed from start of treatment through 30 days after cryoablation treatment (estimated to be 31 days)
Randomized Controlled Trial: Ipsilateral breast cancer recurrence (IBTR) in the treated breast.
Timeframe: At 5 years.