Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan)

Inclusion Criteria: * ≥65 years of age * Admitted to the acute medical department, Hvidovre Hospital * Can cooperate cognitively and physically (patient reported) * Low appetite/anorexia of ageing measures by SNAQ score ≤14 * BMI ≤30 (screening) * Able to read and understand Danish * Postmenopausal defined as missed periods for at least 12 months before the start of the trial Exclusion Criteria: * Regular use of medical cannabis (patient reported) * Use of medical cannabis within 14 days at baseline (patient reported) * Recognized or suspected psychotic illness in the subject or the subjects family (medical record and patient report) * Severe personality disorders (journal) * Significant psychiatric disorder in addition to mild to moderate depression (medical record) * Allergy to the ingredients of Sativex®, placebo and Hexamycin® (patient reported) * Terminal diagnosis (journal) * Liver transplant (journal) * Chronic eGFR ≤15 mL / min2 or dialysis treatment (medical record) * High risk of nephrotoxicity due to existing drug treatment (medical assessment) * Pacemaker (journal) * Epilepsy (journal) * Recurrent seizures (journal) * Uncontrolled hypertension (journal) * Food intolerance to the ingredients in the test meals (patient-reported) * Vegetarian and vegan (patient-reported) * Unwilling to avoid driving for up to 72 hours after administration of Sativex® (patient-reported) * Unwilling to avoid alcohol 24 hours up to test days (patient-reported) * Patients with ascites…