Repetitive Transcranial Magnetic Stimulation in SCA3 Patients

Inclusion Criteria: 1 .Patients with detectable clinical signs and confirmed genetic diagnosis with SCA3. 2\. SCA3 patients aged 20 - 80 years 3. Patients or their family members have informed consent to the study and signed relevant documents Exclusion Criteria: * 1\. Patients who have concomitant epilepsy. 2. History of seizure or heat convulsion. 3. Patients on neuroleptics. 4. History or current unstable hypertension. 5. History of head injury or neurosurgical interventions. 6. History of any metal in the head (outside the mouth). 7. Known history of any metallic particles in the eye, implanted cardiac pacemaker, implanted neurostimulators, surgical clips (above the shoulder line) or any medical pumps. 8\. History of frequent or severe headaches. 9. History of migraine. 10. History of hearing loss. 11. History of cochlear implants 12. History of drug abuse or alcoholism. 13. Pregnancy or not using a reliable method of birth control. 14. Participation in current clinical study.