RecruitingNot Applicable

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment

United States12 participantsStarted 2022-12-08

Plain-language summary

Constraint-Induced Therapy (CI Therapy) is a behavioral approach to neurorehabilitation and consists of multi-components that have been applied in a systematic method to improve the use of the limb or function addressed in the intensive treatment. CI Therapy for the more-affected upper extremity (UE) post-stroke is administered in daily treatment sessions over consecutive weekdays. Sessions include motor training with repeated, timed trials using a technique called shaping, a set of behavioral strategies known as the Transfer Package (TP) to improve the use of the more-affected hand in the life situation, and strategies to remind participants to use the more-affected UE including restraint. Robust improvements in the amount and qualify of use have been realized with stroke participants from mild-to-severe UE impairment.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * At least 6 months post stroke * The ability to demonstrate the minimum UE active movement criteria of 20 degrees of wrist extension from a fully flexed position, 10 degrees of thumb extension or abduction, and 10 degrees of extension of all finger joints. * Mean score of \>2.5 on the Motor Activity Log indicating the participant's use of the more-affected UE. Exclusion Criteria: * Score\< 24 on the Mini Mental State Exam * Inability to answer the MAL questions and/or provide informed consent * The inability to come in to the laboratory setting for treatment.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

45-Item Motor Activity Log (MAL)

Timeframe: At post treatment after 2 weeks of intervention

45-Item Motor Activity Log (MAL)

Timeframe: At 3 months after the end of the treatment

Wolf Motor Function Test (WMFT)

Timeframe: At post treatment after the 2 weeks of intervention

Canadian Occupational Performance Measure (COPM)

Timeframe: At post-treatment after the 2 weeks of intervention

Canadian Occupational Performance Measure (COPM)

Timeframe: At follow-up at 3 months following the end of treatment.

Trial details

NCT IDNCT05492513

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11

Contact for this trial

Mary H Bowman, BS OT

2059340069 mbowman@uab.edu

View on ClinicalTrials.gov More CVA (Cerebrovascular Accident) trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

45-Item Motor Activity Log (MAL)

Timeframe: At post treatment after 2 weeks of intervention

45-Item Motor Activity Log (MAL)

Timeframe: At 3 months after the end of the treatment

Wolf Motor Function Test (WMFT)

Timeframe: At post treatment after the 2 weeks of intervention

Canadian Occupational Performance Measure (COPM)

Timeframe: At post-treatment after the 2 weeks of intervention

Canadian Occupational Performance Measure (COPM)

Timeframe: At follow-up at 3 months following the end of treatment.