Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combina⦠(NCT05490940) | Clinical Trial Compass
UnknownNot Applicable
Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combination With Tisseel - RET
Switzerland74 participantsStarted 2023-03-01
Plain-language summary
Evaluation of sensitivity after primary surgical treatment of digital nerve injuries with microsurgical epineural end-to-end neurorrhaphy alone or in combination with the fibrin glue TisseelĀ®
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Written consent to participate in the study
* Acute digital nerve lesion(s) distal to the superficial arterial arch on one or more fingers that qualify for primary direct end-to-end microsurgical epineural neurorrhaphy
* Age ā„18 years
Exclusion Criteria:
* Lesions that do not allow a tension-free direct suture, partial transections, amputation, re-vascularisation
* Age \< 18 years
* Pre-operation on the injured finger
* Clinical comparison with contralateral finger not possible (e.g. due to amputation).
* Treatment that is known to inhibit the growth/regeneration of nerves impaired or can cause neuropathy - such as chemo- or radiotherapy before or during the whole study
* Systemic and local neurological impairments (polyneuropathy, diabetes mellitus, carpal tunnel syndrome, etc.)
* History of vascular diseases like Raynaud's disease syndrome that affects blood flow or sensation in the upper can affect the extremities
* Known or suspected non-compliance
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, or dementia
* Women who are pregnant (urin pregnancy test) or breast feeding. Female participants who are surgically sterilised / hysterectomised or post-menopausal for longer than 2 years are not considered as being of child bearing potential.
* Previous enrolment into the current study
* Enrolment of the investigator, his/her family members, employees and other dependent persons
* Contraindicatioā¦