Evaluation of the Safety and Efficacy of Voice Prosthesis in Voice Reconstruction After Total Laryngectomy

Inclusion Criteria: * The age is greater than 18 years; the gender is not limited * Performed total laryngectomy; * No voice prosthesis has been installed * Be able to take care of themselves mentally and physically, and have good hand coordination ability * With healthy wall sharing with trachea and esophagus * The patient has a desire to restore articulation function * Can speak Mandarin and have a certain reading ability (equivalent to primary school education) * The subject is fully aware of the benefits and risks of this trial and is willing to participate in and sign the informed consent form Exclusion Criteria: * There is serious respiratory system disease or defect * There is a serious skin disease in the tracheostoma * Obvious intelligence and mental disorder * Tracheostoma is narrow and needs cannula implantation * Patients with limitation of mouth opening and other subjects with dyslalia or language disorders (such as subjects with sequelae of cerebral infarction, etc.) * Patients with severe respiratory disease, cardiopulmonary disease (e.g., severe arrhythmia, persons with slow ventricular rate (ventricular rate \<50 beats/ min), acute phase of myocardial infarction and severe heart failure), disturbances of blood coagulation (coagulation index PT, APTT, INR\> 1.5 times of the normal upper limit), septicemia and other patients not suitable * Patients with severe diseases of liver and renal function (liver function index, alanine aminotransferase (ALT), asparta…