Study of C-TIL052A Cell Therapy in Advanced Cervical Cancer (NCT05475847) | Clinical Trial Compass
UnknownPhase 1
Study of C-TIL052A Cell Therapy in Advanced Cervical Cancer
China20 participantsStarted 2022-07
Plain-language summary
A study that aimed to assess the safety and anti-tumor activity of C-TIL052A cell therapy in subjects with persistent, recurrent and/or metastatic cervical cancer.
Who can participate
Age range
18 Years – 70 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Aged 18 to 70 years at screening
. Voluntary participation and able to sign the informed consent form
. Patients with histologically confirmed persistent, recurrent and/or metastatic cervical cancer who failed the standard treatment.
. Has access to tumor tissue and can isolate ≥1.0g of tumor tissue mass for the preparation of autologous tumor infiltrating lymphocytes
. At least one measurable target lesion (per RECIST v1.1)
. ECOG performance status score: 0\~1
. Expected survival ≥ 3 months
. Negative serum or urine pregnancy test results for females of child-bearing age at screening
Exclusion criteria
. Uncontrolled CNS disease, severe cerebrovascular disease or obvious neurological symptoms (including mental disease)
. Symptomic chronic obstructive pulmonary disease or persistent asthma
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Adverse Events (AE)
Timeframe: up to 12 months or through study completion