Ligation of Anterior Internal Iliac Artery With Conservative Management of Partial or Focal Place… (NCT05471102) | Clinical Trial Compass
CompletedNot Applicable
Ligation of Anterior Internal Iliac Artery With Conservative Management of Partial or Focal Placenta Accreta Spectrum
Egypt44 participantsStarted 2022-07-03
Plain-language summary
The patients will be divided into 2 groups:
Group (A) - Study group: Cases managed by lower segment resection with ligation of the anterior division of the internal iliac artery
Group (B) - Control group: Cases managed by lower segment resection without ligation of the anterior division of the internal iliac artery
The following operative details will be recorded:
* Estimation of total blood loss
* Pre and 24-h post-operative hemoglobin (g/dl).
* The need for blood transfusion and its amount intra or postoperative will be recorded
* Operative time and postoperative hospital stay will be recorded.
* Close post-operative monitoring of the patients' vital signs, drain output, and urine output
* Presence or absence of intraoperative complications; bladder, ureteric, bowel, or vascular injuries will be recorded.
* Monitoring for postoperative morbidities
Who can participate
Age range
20 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age: 20-40 years old.
* Pregnancy of singleton living fetus.
* Previous one or more cesarean sections.
* Gestational age: \> 36 weeks.
* Elective termination of pregnancy.
* Cases not requiring preoperative blood transfusion.
* Cases with focal area of placental adherence or invasion leaving sufficient healthy myometrial tissue for uterine repair and preservation.
* The following ultrasound markers such as "loss of clear retroplacental translucency", "myometrial thinning", "abnormal lacunae", "irregular bladder wall", "utero-vesical hypervascularity".
Exclusion Criteria:
* Multifetal pregnancy.
* More than four previous sections.
* Emergency termination of pregnancy due to antepartum hemorrhage, placental separation or rupture uterus.
* Intrauterine fetal death.
* Women with history of any medical disorder with pregnancy eg. Gestational diabetes and hypertension.
* Premature rupture of membranes.
* Cases misdiagnosed as placenta accreta by ultrasound preoperatively, and spontaneous full placental separation occurred intraoperative. "will be excluded before randomization"
* Cases with PAS with total invasion involving all placental lobules.
* Cases who will be managed by cesarean hysterectomy due to uncontrolled intraoperative bleeding.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.