UnknownNot Applicable

Tracheal Positive Pressure During High Flow Nasal Oxygen Administration in Critically Ill Patients: a Physiologic Study.

Italy20 participantsStarted 2023-04

Plain-language summary

High flow nasal cannula administration in critically ill patients is frequently used to improve acute respiratory failure or to prevent respiratory failure after extubation. It acts generating a mild positive pressure in the airways and by reducing respiratory effort of patients. However to the best of our knowledge, no study to date has directly measured the amount of positive pressure generated in the trachea of patients. The primary aim, therefore, of this study measures this positive pressure after extubation in critically ill patients.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: CRITICALLY ILL PATIENTS AFTER MECHANICAL VENTILATION LASTED AT LEAST 72 HOURS * age 18-80 years Exclusion Criteria: * COPD stage \>1 according to GOLD classification * end stage organ disease (liver, kidney, heart, lung) * neuromuscular disease * neoplasm * previous tracheostomy * obesity with BMI \> 35 Kg/m2 * non collaborative patient

What they're measuring

HFNC-PEEP

Timeframe: 3 HOURS

Trial details

NCT IDNCT05467332

SponsorAzienda Sanitaria-Universitaria Integrata di Udine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-09

Contact for this trial

Cristian Deana, MD

+390432552410 cristian.deana@asufc.sanita.fvg.it

View on ClinicalTrials.gov More Acute Respiratory Failure trials