Liquid Biopsy for Early Non-small Lung Cancer Detection

Indeterminate pulmonary nodule study cohort * Inclusion criteria: Patients undergoing a biopsy of an indeterminate lung nodule by surgical excision, bronchoscopic biopsy or Interventional Radiology directed biopsy * Exclusion criteria: No known concurrent cancer Known lung cancer for surgical resection study cohort * Inclusion criteria: Patients with known non-small cell lung cancer who will have surgical resection for treatment * Exclusion criteria: N/A Healthy volunteer cohort * Inclusion criteria: Healthy persons * Exclusion criteria: No known current cancer or history of cancer within 5 years Benign lung disease cohort * Inclusion criteria: Patients with the following categories of benign lung disease: COPD/emphysema, Granulomatous infection, Interstitial lung disease including pulmonary fibrosis and interstitial lung disease. * Exclusion criteria: N/A