The purpose of this study to evaluate the effects of naltrexone plus lemborexant augmentation compared to naltrexone plus placebo on cue-induced and non-cued alcohol cravings in people with alcohol use disorder and insomnia. Our secondary goals are to evaluate the effects of lemborexant plus naltrexone combination on sleep quality using self-report questionnaires and actigraph data, depression, anxiety, and suicidal ideation.
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Cue-induced Alcohol Cravings Using the Alcohol Urge Questionnaire
Timeframe: Baseline to last available post-baseline assessment (2 to 4 weeks after randomization)
Non-Cued Alcohol Cravings Using the Penn Alcohol Craving Scale
Timeframe: Baseline to study endpoint (2 to 4 weeks after randomization)