Evaluation of the Effect of Spry Belt Treatment on Bone Turnover Marker Profile

Inclusion Criteria: * Female * Had her last menstrual period at least one year prior to the time of study enrollment * Has low bone mass as defined by a DXA T-score between -1.0 and -2.49 for the femoral neck, total femur, or lumbar spine * Is 50 years of age or older * Can walk and stand without an assistive device * Is able to provide informed consent * Is able to understand spoken and written English * Is capable and willing to follow all study-related procedures Exclusion Criteria: * Has a bone mineral density (BMD) at the femoral neck, total femur, or lumbar spine of T score ≤ -2.5 (defined by DXA) * Has a 10-year probability of major fracture \>20% or hip fracture \>3% based on results of the Fracture Risk Assessment (FRAX) Tool (at screening) * Is currently taking or has taken oral bisphosphonates or other prescription osteoporosis medications in the past 24 months, or estrogen replacement therapy, glucocorticosteroids, dehydroepiandrosterone, tenofovir disoproxil fumarate, or other drugs affecting bone in the past 3 months * Has had at least one fracture or at least one major surgery within the past 6 months * Smokes \>10 cigarettes per day over the past 6 months * Has had an average of 14 alcoholic drinks per week over the past 6 months * Has type I diabetes * Has a history of severe renal disease or kidney failure * Has had bariatric surgery * Has been diagnosed with chronic renal disease, cirrhosis, multiple myeloma, neuromuscular disease, osteomalacia, Paget's …