This phase II trial studies the effect of DNA plasmid based vaccine (STEMVAC) in treating patients with patients with stage IB-III triple negative breast cancer. STEMVAC may wake up the immune system in patients who have had a diagnosis of triple negative breast cancer and have been treated. STEMVAC targets proteins that are expressed on breast cancer cells and works by boosting the immune system to recognize and destroy the invader cancer cell proteins that are causing the disease. The purpose of this trial is to test the immune system's response to STEMVAC.
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Cellular immune response: incidence
Timeframe: At 1 month after 3rd vaccination
Cellular immune response: incidence
Timeframe: At 10 months after 3rd vaccination
Cellular immune response: magnitude
Timeframe: At 1 month after 3rd vaccination
Cellular immune response: magnitude
Timeframe: At 3 months after 3rd vaccination
Cellular immune response: magnitude
Timeframe: At 9 months after 3rd vaccination
Cellular immune response: magnitude
Timeframe: At 10 months after 3rd vaccination