Atropine has a ciliary muscle-paralysing effect and causes hyperopic drift. Besides, atropine has been proven to slow the progression of myopia. Many studies have suggested that atropine can increase the thickness of the choroid. However, few studies have discussed changes in the ciliary muscle after treatment with atropine or other cycloplegic agents. This study aimed to assess the difference in ciliary muscle morphology before and after two different cycloplegic agents and to analyze the correlation between the changes of ciliary muscle biological parameters and the changes of eye axis, spherical equivalent, lens diopter, choroidal thickness, etc. One hundred and forty-four children would be randomly assigned 1:1 to the 1% atropine group and the tropicamide group. This study might provide clinical evidence for the role of regulatory factors in the occurrence and development of myopia.
Age range
3 Years – 12 Years
Sex
ALL
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ciliary thickness parameters
Timeframe: before intervention
ciliary thickness parameters
Timeframe: immediately after the last intervention
the distance between ciliary muscle apex and scleral spur
Timeframe: before intervention
the distance between ciliary muscle apex and scleral spur
Timeframe: immediately after the last intervention