Connectivity in Cranioplasty

Inclusion Criteria: * Diagnosis of sABI, a neurological condition due to a severe acquired brain damage (i.e., traumatic brain injury, ischemic stroke, hemorrhagic stroke) with a coma lasting at least 24 hours, according to a Glasgow Coma Scale equal or lower than 8 and/or complex and severe neurological disabilities treatable only in high specialty neurehabilitative settings. * Early DC, within 24 h; * Age between 18 and 75 years; * Intra-hospital rehabilitation setting (ordinary hospitalization or day hospithal); * Informed consent agreement. Exclusion Criteria: * Medical instability at enrollment, defined as the acute onset of an unexplained derangement of vital parameters (i.e., temperature, blood pressure, pulse rate, respiratory rate, oxygen saturation, level of responsiveness) outside the normal range (for example, fever, acute internist conditions, etc.) and/or the onset of any new medical condition requiring unexpected additional diagnostic procedures and treatments (for example, severe pain, reduction of urinary output, etc.); * Post-traumatic agitation; * Dehiscence, in progress, of the DC surgical wound; * CP already performed; * Magnetic Resonance Imaging (MRI) absolute contraindications.