TOLER-ENT Study: A Study to Investigate the Tolerance of the High Energy, High Protein Formula Sondalis® HP 2 kcal

Inclusion Criteria: * Men or women aged ≥18 years, * Being under EN with polymeric HPHE product with or without fibre (=HPHE), * Stable caloric prescription during HEN for at least one month, * Patient with at least a score of 2 on at least 1 item of tolerance questionnaire, * Investigators' judgement to change to HPHE concentrated, * HEN is planned for ≥ 8 weeks, * Life expectancy ≥ 3 months. * Patient or his/her primary caregiver was required to be able to understand the study and to be fully free to participate in it, * Patient having signed an informed consent, * Patient registered with a social security scheme, * Patient willing to adhere to study procedures, Exclusion Criteria: * Pregnancy or breastfeeding, * Being either under PN or ONS, * Acute intestinal disease such as gastric ulcer, gastritis, gastroparesis, * Patient under prokinetic agents during the study phase, * Patient receiving antibiotic, chemotherapy in the 7 days prior to inclusion, * Patient receiving radiation treatment except head and neck location, * Patient expected to receive chemotherapy or radiation treatment during the study except head and neck location , * Severe infectious disease and/or fever \> 38,5°C, * Emergent hospitalization within last month, * Known allergy or intolerance to any of the Sondalis® HP 2kcal with or without fibre ingredients, * Previous treatment with HPHE concentrated at home (2kcal), * Current participation in another intervention study or participation in a previous …