WithdrawnNot Applicable

Virtual Planning of ALT Flap

Stopped: Fellow left UF study never started

0Started 2023-09

Plain-language summary

This study evaluates the advantage of using preoperative virtual planning to design the volume and shape of antero-lateral thigh free flap tissue transfer to reconstruct tongue defects resulted from carcinoma resection and see how this would affect tongue form and speech function.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Patients with primary tongue squamous cell carcinoma (SCC) requiring hemi-glossectomy.
✓. No alveolar ridge involvement by the tumor process.
✓. Planned to undergo tongue reconstruction using ALTF.
✓. Patients with a depth of invasion more than 10mm but not crossing midline according to the classification of Ansarin et. al., we perform type IIIA glossectomy.

Exclusion criteria

✕. Medically unfit patients; those who are not good candidates for long microvascular surgical reconstructive procedures e.g.: advanced Cardiopulmonary diseases.
✕. Recurrent tongue carcinoma.
✕. Patients with lesions invading the alveolar ridge.
✕. Missing or non-compliance for imaging investigations.
✕. Patients underwent preoperative adjuvant therapies.
✕. No children will be involved in this study.

What they're measuring

Prospectively evaluate a new method of virtually planned ALTF and changes in flap volume for the reconstruction of tongue defects following hemi-glossectomy

Timeframe: Changes in flap volume/cm3 will be measured after one and six months after surgery where the preoperative virtually planned volume/cm3 is being the base line.

Trial details

NCT IDNCT05424328

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09

View on ClinicalTrials.gov More Tongue SCC trials