Following the initiation of Doravirine (DOR) regimen among people living with HIV (PLWH), the study will aim to assess effectiveness, discontinuation, and resistance over the 12-month period. Retrospective data from 500 patients is planned to be collected from 6 - 10 European sites. Cohort 1 : 400 patients, 100 treatment naïve and 300 virally suppressed patients switching from a 1st or second line treatment, Cohort 2: 50 patients with NNRTI mutations (other than DOR), Cohort 3: 50 patients with NNRTI mutations (including DOR). The study will be conducted through collaboration with the NEAT ID Network, a well-established network of clinical sites across Europe.
Age range
18 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Proportion virologically suppressed patients at week 48 who have remained on DOR.
Timeframe: Week 48 after DOR initiation
Proportion of patients with virologic failure (Cohort 1 - treatment naive)
Timeframe: on or after week 48 after DOR initiation
Proportion of patients with virologic failure (Cohort 2 - treatment suppressed)
Timeframe: up to 12 months after initiation of DOR
Proportion of patients switched for reasons other than virological failure.
Timeframe: up to 12 months after initiation of DOR