Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mos… (NCT05394597) | Clinical Trial Compass
UnknownNot Applicable
Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mosquitos in Louisiana
United States20 participantsStarted 2021-06-11
Plain-language summary
To determine the efficacy and duration of protection of two topically applied insect repellent products at preventing landing by mosquitos. The study will follow the EPA Product Performance Test Guidelines1. It is intended to test the products against natural populations of mosquito species of public health importance within the genera Aedes, Anopheles, and Culex, and to replace data from one site previously tested in Florida with data from a site in Louisiana with adequate landing pressure from target mosquito species of public health relevance.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Able and willing to give fully informed consent;
* Male or female;
* Aged 18 to 55 years;
* Consider themselves to be in good general health, and specifically:
* Not aware of having any cardiovascular or respiratory disorder (whether active or inactive)
* No previous anaphylaxis
* Not aware of having a compromised immune system
* Non-smokers or willing to refrain for 24 hours prior to and during each test;
* Willing to undergo a mosquito attraction test (putting an arm into a cage of mosquitos)
* Able to speak and understand English
* Able to stand outside for periods of at least 5 minutes at a time
* Able to understand and comply with the study procedures, including:
* Willing to complete mosquito landing/aspirating training
* Able to withstand exposing the lower leg to mosquitos for periods of at least 5 minutes at a time
* Able to operate an aspirator
Exclusion Criteria:
* Participated in any other intervention study in the previous 3 months
* Participated in a biting insect test as part of the current study in the previous 72 hours
* Employees, managers, and spouses of employees of the LSU and of the study Sponsor (LivFul, Inc.)
* Students of the Study Director or any other LSU faculty/researchers involved in the study
* Individuals suspected or known to be sensitive or allergic to, or phobic of, mosquito bites
* Women who are pregnant, nursing or intending to become pregnant during the course of the study
* Individuals with localize…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Median Complete Protection Time
Timeframe: 14 hours
Trial details
NCT IDNCT05394597
SponsorLouisiana State University Health Sciences Center in New Orleans