A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough

Inclusion Criteria: * Adults ≥18 to ≤80 years of age * History of refractory or unexplained chronic cough * Historical Chest radiograph or CT scan that does not demonstrate any abnormality considered to be significantly contributing to chronic cough * Not pregnant, breastfeeding, or lactating and agree to use a highly effective method of acceptable contraceptive for the trial duration, if applicable * Agree to discontinue antitussive medications for the trial duration Exclusion Criteria: * Current smoker (including cannabis products) or previous smoker having recently given up smoking or has a history of smoking of \>20 pack-years * History of significant cardiovascular disease or any clinically significant abnormalities in rhythm or conduction * History or presence of significant hepatic disease or any other condition known to interfere with absorption, distribution, metabolism, or excretion of drugs. * History of any malignancy within 5 years of screening except for basal cell or squamous cell in situ skin carcinomas or carcinoma in situ of the cervix that has been treated with no evidence of recurrence. * Recent history of drug or alcohol abuse or a positive urine drug test at screening * Positive serology test for Hepatitis B virus (HBV), Hepatitis C virus (HCV), or HIV-1 and HIV-2 * Currently taking an angiotensin converting enzyme inhibitor (ACEI) or has used an ACEI within 3 months of Screening.