Novel Dental Gel as an Adjunct to Scaling and Root Planing (NCT05384132) | Clinical Trial Compass
RecruitingNot Applicable
Novel Dental Gel as an Adjunct to Scaling and Root Planing
United States76 participantsStarted 2022-10-14
Plain-language summary
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
Who can participate
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female subjects at least 18 years of age.
* Subject must be willing and able to provide written informed consent.
* Available during the course of the study.
* Must have minimum of 20 natural teeth, excluding third molars.
* Must have at least 20 BOP sites, excluding third molars.
* Stage II or III, Grade B periodontitis with at least 4 teeth with a minimum PD of 5 mm and minimum CAL of 3mm.
* No antibiotic therapy for periodontal disease or chronic use of anti-inflammatory drugs (NSAIDs) within the past month of Baseline, or during the study.
* Must not have received definitive treatment (i.e., SRP or periodontal surgical therapy) for periodontitis in the last one year.
* Subject must be willing and able to comply with study visits as described in the protocol.
* Subjects must be available for follow up on the telephone.
* Able to read and understand the consent form in English
Exclusion Criteria:
* • Pregnancy or breast feeding.
* Medical condition that requires pre-medication prior to dental procedures.
* Systemic conditions and use of medications that may affect periodontal tissues.
* Severe dental disease characterized multiple decayed, untreated dental sites.
* Presence of orthodontic appliances.
* Diseases of oral soft or hard tissues.
* Participating in another clinical trial currently or in the month preceding this study.
* Stage IV and/or Grade C periodontitis.
* Vertical bone defects 4mm or grea…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.