Companion for CAR-T Web App During Chimeric Antigen Receptor T-cell Therapy (NCT05362331) | Clinical Trial Compass
WithdrawnNot Applicable
Companion for CAR-T Web App During Chimeric Antigen Receptor T-cell Therapy
Stopped: Contract issues
0Started 2023-01-01
Plain-language summary
The complex logistics and unique toxicities of chimeric antigen receptor T-cell (CAR-T) therapy require intensive patient education and careful monitoring. The Companion for CAR-T (CC) web app may be able to assist with patient education and preparation, communication between patients and their multidisciplinary teams, and home-based toxicity monitoring.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of a hematologic malignancy (including any plasma cell dyscrasia, any type of lymphoma, or any type of leukemia).
* Planned receipt of an FDA-approved CAR-T therapy at University of California, San Francisco (UCSF) as standard of care.
* Patient proficiency in spoken and written English.
* Caregiver proficiency in spoken and written English.
* Age \>= 18 years old
Exclusion Criteria:
* FDA-approved CAR-T therapy being administered as part of a prospective industry-sponsored trial, for example registrational trials of CAR-T therapy versus salvage chemotherapy or CAR-T therapy as an off-label line of therapy.
\*However, patients who receive an FDA-approved CAR-T therapy through an Expanded Access Program for non-conforming products (or any observational, non-interventional analysis of CAR-T products) are eligible.
* Lack of ownership of a personal computing device, tablet device, or smartphone.
* Refusal of patient and/or caregiver to sign up for a UCSF MyChart account.
\*Participants and caregivers who do not have a MyChart account at enrollment but are willing to create one will receive assistance from the study team to do so.
* Any serious and/or unstable pre-existing medical, psychiatric, or other condition that could - in the opinion of the study's Principal Investigator (PI) - interfere with provision of informed consent or compliance with study procedures.
What they're measuring
1
Percentage of participants who access all four CC web application modules at least once
Timeframe: Up to 6 months
2
Percentage of participants agreeing or strongly agreeing with helpfulness of CC web application.