TReating Incontinence for Underlying Mental and Physical Health

Inclusion Criteria: * Aged 60 years or older at the time of enrollment * Female sex at birth, without surgical or hormonal gender re-assignment therapy * Able to walk to the bathroom and use the toilet without assistance * Report urinary incontinence starting at least 3 months prior to screening * Report that at least half of incontinence episodes occur with a sudden or strong sensation of urgency * Report 2 or more urgency incontinence episodes over a 7-day period * Willing to provide informed consent and adhere to study procedures throughout the length of the study Exclusion Criteria: * Prior clinician diagnosis of dementia, or a Montreal Cognitive Assessment (MOCA) score of 17 or lower on screening cognitive evaluation * Current use of anticholinergic, beta-3-adrenergic agonist, or other medication designed to improve urgency incontinence symptoms, or use in the past 1 month * Initiation, discontinuation, or dose change of dementia medications (such as donepezil, galantamine, memantine, rivastigmine) in the past 1 month (but candidates on stable doses are eligible) * Initiation, discontinuation, or dose change of other drugs with strong anticholinergic effects (based on the Beers List) in the past 1 month (but candidates on stable doses are eligible) * Initiation, discontinuation, or dose change of other drugs that can affect urinary frequency, including diuretics, in the past 1 month (but candidates on stable doses are eligible) * Current urinary tract infection (UTI) …