Improving Pain Disability With the Use of Oral Cannabinoids (NCT05351905) | Clinical Trial Compass
CompletedNot Applicable
Improving Pain Disability With the Use of Oral Cannabinoids
Canada51 participantsStarted 2022-11-22
Plain-language summary
The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain. At the end of this 3 month study, investigators will gather information on how easy it is for patients to enroll and complete the entire study. The results of this pilot study will help the study team design a larger randomized controlled trial.
Who can participate
Age range
25 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age ≥ 25 years
. Able to understand and read English
. Experiencing chronic, non-palliative pain
Exclusion criteria
. Use of nabilone, nabiximols or cannabis in the 30 days preceding study recruitment
. Known allergy to cannabis or any cannabinoid
. Serious ongoing medical issues (i.e., lung, liver, kidney or heart disease) that in the opinion of the Investigator would compromise the safety of the patient
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Feasibility outcome: pertaining to the patients recruitment
Timeframe: Through study completion, an average of 1 year
2
Feasibility outcome: pertaining to adherence to intervention
Timeframe: Up to 12 weeks post-treatment
3
Feasibility outcome: pertaining to withdrawal from study
Timeframe: Up to 12 weeks post-treatment
4
Feasibility outcome: pertaining to questionnaire data
Timeframe: Up to 12 weeks post-treatment
5
Feasibility outcome: the rate of unintentional unblinding
. Current uncontrolled serious mental disorders such as schizophrenia, or psychosis
. Currently pregnant or breast-feeding (a negative urine pregnancy test must be obtained for women of child bearing potential during pretreatment evaluation)
. Men and women planning to start a family in the next 12 weeks
. Has declared a current alcohol or substance use disorder (excluding opioid use disorder)