Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synthesis. Although there are clear health-related benefits of physical activity, little is known about how resistance exercise, as opposed to endurance exercise, can reduce the risk of metabolic disorders, particularly in women. The goal of the proposed study is to investigate the effectiveness of resistance training to improve basal and stimulated fat metabolism in postmenopausal women with obesity and pre-diabetes, potentially serving as a viable and practical approach to prevent the onset of type 2 diabetes.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Change from baseline subcutaneous abdominal adipose tissue glycerol concentration at 12 weeks
Timeframe: 12 weeks of resistance or endurance training
Change from baseline gluteal adipose tissue glycerol concentration at 12 weeks
Timeframe: 12 weeks of resistance or endurance training
Change from baseline whole-body lipolysis at 12 weeks
Timeframe: 12 weeks of resistance or endurance training